Genetics of Large Populations and Association Studies
نویسندگان
چکیده
The distribution of genetic variability in natural populations is the result of a number of evolutionary factors. We present concepts on the genetics of large populations, with special reference to association studies. Particular issues related to selection, mutation and genetic load, or migration in spatial models are not treated here. Genetic drift is assumed to be negligible, unless otherwise stated. (See Fitness and Selection; Genetic Drift; Genetic Load; Population Genetics: Historical Aspects; Mutation Rates: Evolution.)
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تاریخ انتشار 2005